Itchy cheeks
I play a female character in our long running Fate campaign. This would be more mysterious if Maya weren't about as far from conventionally feminine as you can get (I like to think she's female because she looked down at her parts and never felt the need to question it)
But a fun detail my DM (and boyfriend) added was after having a reverse blood transfusion, she woke up to find the sketchy doctor had also taken a part of her liver. But no worries, he'd given her a serum to promote regeneration. And Maya's face started to itch as her facial hair began to grow in at an accelerated rate.
And it made me really happy.